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1

1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Villhauer, Edwin B., Brinkman, John A., Naderi, Goli B., Burkey, Bryan F., Dunning, Beth E., Prasad, Kapa, Mangold, Bonnie L., Russell, Mary E., Hughes, Thomas E.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 230 KB

english, 2003

2

Facile and practical synthesis of a cannabinoid-1 antagonist via regio- and stereoselective ring-opening of an aziridinium ion

Edwin B. Villhauer, Wen-Chung Shieh, Zhengming Du, Kevin Vargas, Lech Ciszewski, Yansong Lu, Michael Girgis, Melissa Lin, Mahavir Prashad

Journal:

Year:

2009

Language:

english

File:

PDF, 687 KB

english, 2009

3

1-[2-[(5-Cyanopyridin-2-yl)amino]ethylamino]acetyl-2-(S)-pyrrolidinecarbonitrile: A Potent, Selective, and Orally Bioavailable Dipeptidyl Peptidase IV Inhibitor with Antihyperglycemic Properties

Villhauer, Edwin B., Brinkman, John A., Naderi, Goli B., Dunning, Beth E., Mangold, Bonnie L., Mone, Manisha D., Russell, Mary E., Weldon, Stephen C., Hughes, Thomas E.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 59 KB

english, 2002

4

NVP-DPP728 (1-[[[2-[(5-Cyanopyridin-2-yl)amino]ethyl]amino]acetyl]-2-cyano-(S)-pyrrolidine), a Slow-Binding Inhibitor of Dipeptidyl Peptidase IV

Hughes, Thomas E., Mone, Manisha D., Russell, Mary E., Weldon, Stephen C., Villhauer, Edwin B.

Journal:

Year:

1999

Language:

english

File:

PDF, 116 KB

english, 1999

5

The individual enantiomers of cis-cromakalim possess K+ channel opening activity

Ulrich Quast, Edwin B. Villhauer

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1993

Language:

english

File:

PDF, 590 KB

english, 1993

6

A Scalable Synthesis of a 1,7-Naphthyridine Derivative, a PDE-4 Inhibitor

Jiang, Xinglong, Lee, George T., Villhauer, Edwin B., Prasad, Kapa, Prashad, Mahavir

Journal:

Organic Process Research & Development

Year:

2010

Language:

english

File:

PDF, 446 KB

english, 2010

7

A Concise Synthesis of a Novel Insulin-Like Growth Factor I Receptor (IGF-IR) Inhibitor †

Slade, Joel, Bajwa, Joginder, Liu, Hui, Parker, David, Vivelo, James, Chen, Guang-Pei, Calienni, John, Villhauer, Edwin, Prasad, Kapa, Repič, Oljan, Blacklock, Thomas J.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 278 KB

english, 2007

8

Metal-catalyzed stereospecific Michael reaction equivalent

Godleski, Stephen A., Villhauer, Edwin B.

Journal:

Journal of Organic Chemistry

Year:

1984

Language:

english

File:

PDF, 1006 KB

english, 1984

9

Kinetically Controlled Diastereoselective Synthesis of CPS124, a Carnitine Monothiophosphate

Prasad, Kapa, Xu, David D., Tempkin, Orin, Villhauer, Edwin B., Repič, Oljan

Journal:

Organic Process Research & Development

Year:

2003

Language:

english

File:

PDF, 109 KB

english, 2003

10

[Annual Reports in Medicinal Chemistry] Volume 36 || Chapter 19. DPP-IV inhibition and therapeutic potential

Villhauer, Edwin B.

Year:

2001

Language:

english

File:

PDF, 817 KB

english, 2001

11

Antidiabetic agents: a new class of reversible carnitine palmitoyltransferase I inhibitors

Anderson, Robert C., Balestra, Michael, Bell, Philip A., Deems, Rhonda O., Fillers, William S., Foley, James E., Fraser, James D, Mann, William R., Rudin, Markus, Villhauer, Edwin B.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 415 KB

english, 1995

12

Application of a transition-metal-mediated stereospecific Michael reaction equivalent to the synthesis of alloyohimbone

Godleski, Stephen A., Villhauer, Edwin B.

Journal:

Journal of Organic Chemistry

Year:

1986

Language:

english

File:

PDF, 800 KB

english, 1986

13

Conformation of [1-13C,15N]Acetyl-L-carnitine. Rotational-Echo, Double-Resonance Nuclear Magnetic Resonance Spectroscopy

Anderson, Robert C., Gullion, Terry, Joers, Jim M., Shapiro, Michael, Villhauer, Edwin B., Weber, Hans Peter

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 1.27 MB

english, 1995

14

Synthesis of the CDE ring system of the ginkgolides

Villhauer, Edwin B., Anderson, Robert C.

Journal:

Journal of Organic Chemistry

Year:

1987

Language:

english

File:

PDF, 624 KB

english, 1987